2015). These experiments, taken together, suggest that, Though a direct activation of GPR55 or PPAR‐α occurs, PEA can deliver its anti‐inflammatory motion in the intestine also through oblique activation of CB1 and CB2 receptors, in all probability because of the flexibility of the compound to potentiate the action of endocannabinoids at these
Abstract Persistent soreness is A significant supply of morbidity for which there are minimal helpful remedies. Palmitoylethanolamide (PEA), a The natural way developing fatty acid amide, has shown utility in the remedy of neuropathic and inflammatory pain. Emerging studies have supported a achievable role for its use from the treatment method of S
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